Estimate Adult GFR With the Race-Free 2021 Creatinine Equation

How to Use This Tool

Reproduce the adult race-free CKD-EPI creatinine equation from age, sex code and standardized creatinine. Online results differ when they silently use the older race-based equation, non-standardized creatinine or different units.

What CKD-EPI 2021 eGFR actually establishes

NKF identifies the 2021 race-free equation by name and recommends standardized creatinine; eGFR remains an estimate, not measured GFR. The page returns estimated gfr in ml/min/1.73 m² from the measurements named below; CKD-EPI 2021 eGFR does not verify how they were collected or combine them with symptoms, examination findings and medical history.

Equation and input contract for CKD-EPI 2021 eGFR

eGFR = 142 × min(Scr/k,1)^alpha × max(Scr/k,1)^−1.200 × 0.9938^age × 1.012 if female, using NKF sex-specific k and alpha. The required entries are Age, Serum creatinine, Sex code: 0 female, 1 male; values should come from the same dated observation, specimen or record unless a label explicitly calls for different dates.

• For CKD-EPI 2021 eGFR, Age uses the example 55 years; replace it with the value and unit from the same record.
• For CKD-EPI 2021 eGFR, Serum creatinine uses the example 1 mg/dL; replace it with the value and unit from the same record.
• For CKD-EPI 2021 eGFR, Sex code: 0 female, 1 male uses the example 0 code; replace it with the value and unit from the same record.

Using estimated gfr in ml/min/1.73 m² safely

Compare with the equation printed by the laboratory and discuss kidney trends, urine albumin and clinical context with a licensed clinician. For CKD-EPI 2021 eGFR, an unexpected answer should prompt a check of units, dates, transcription and the original measurement method. Do not adjust medicine, feeding, fluids, exercise, screening or treatment to make the result match an expected value.

The page-specific limit of CKD-EPI 2021 eGFR

This adult equation is not for children, pregnancy, rapidly changing kidney function, unusual muscle mass or medication dosing without professional review. Preserve that limitation with any saved estimated gfr in ml/min/1.73 m². A reference interval or action threshold still depends on the patient, collection method, laboratory and clinical setting, none of which this arithmetic selects automatically.

Evidence reviewed for CKD-EPI 2021 eGFR

The attached reference is National Kidney Foundation — CKD-EPI Creatinine Equation (2021). It supports the equation, definition or measurement practice used for estimated gfr in ml/min/1.73 m², while the original report and a licensed pediatrician, physician, pharmacist or other relevant professional remain authoritative for interpretation.

Emergency boundary

Do not use a calculator during a possible emergency. Severe breathing difficulty, blue or gray color, seizure, fainting, new confusion, stroke symptoms, inability to wake or rapid deterioration require urgent local medical help.

Privacy and repeatability for CKD-EPI 2021 eGFR

CKD-EPI 2021 eGFR runs in the current browser tab without requesting a name, login or medical-record connection. Keep identifying details out of the fields, preserve the original units and remember that extra decimal places cannot repair an uncertain measurement.